Barbre, Kira A.Jentes, Emily S.Drobeniuc, JanKamilli, SaleemHamer, Davidson H.Barnett, Elizabeth D.2018-08-302018-08-3020172017-01Kira A. Barbre, Emily S. Jentes, Jan Drobeniuc, Saleem Kamili, Davidson H. Hamer, Elizabeth D. Barnett. American Journal of Tropical Medicine and Hygience. 2017 Jan; 96(4):929-934. 10.4269/ajtmh.16-0727https://hdl.handle.net/2144/31118We determined the prevalence of IgG antibodies to hepatitis E virus (anti-HEV IgG) among travelers attending Boston-area travel health clinics from 2009 to 2010. Pre-travel samples were available for 1,356 travelers, with paired pre- and post-travel samples for 450 (33%). Eighty of 1,356 (6%) pre-travel samples were positive for anti-HEV IgG. Compared with participants who had never lived in nor traveled to a highly endemic country, the pre-travel prevalence odds ratio (POR) of anti-HEV IgG among participants born in or with a history of previous travel to a highly endemic country was increased (POR = 4.8, 95% CI = 2.3–10.3 and POR = 2.6, 95% CI = 1.4–5.0, respectively). Among participants with previous travel to a highly endemic country, anti-HEV IgG was associated with age > 40 years (POR = 3.7, 95% CI = 1.3–10.2) and travel history to ≥ 3 highly endemic countries (POR = 2.7, 95% CI = 1.2–5.9). Two participants may have contracted HEV infection during their 2009–2010 trip.en-USCopyright © 2017 by The American Society of Tropical Medicine and HygieneHepatitis EBoston, MassachusettsTropical medicineTravel medicineArticle10.4269/ajtmh.16-0727