Jasinska, Anna J.Zelaya, IvetteService, Susan K.Peterson, Christine B.Cantor, Rita M.Choi, Oi-WaDeYoung, JosephEskin, EleazarFairbanks, Lynn A.Fears, ScottFurterer, Allison E.Huang, Yu S.Ramensky, VasilySchmitt, Christopher A.Svardal, HannesJorgensen, Matthew J.Kaplan, Jay R.Villar, DiegoAken, Bronwen L.Flicek, PaulNag, RishiWong, Emily S.Blangero, JohnDyer, T.D.Bogomolov, MarinaBenjamini, YoavWeinstock, George M.Dewar, KenSabatti, ChiaraWilson, Richard K.Jentsch, J. DavidWarren, WesleyCoppola, GiovanniWoods, Roger P.Freimer, Nelson B.2018-05-142018-05-142017-12Anna J Jasinska, Ivette Zelaya, Susan K Service, Christine B Peterson, Rita M Cantor, Oi-Wa Choi, Joseph DeYoung, Eleazar Eskin, Lynn A Fairbanks, Scott Fears, Allison E Furterer, Yu S Huang, Vasily Ramensky, Christopher A Schmitt, Hannes Svardal, Matthew J Jorgensen, Jay R Kaplan, Diego Villar, Bronwen L Aken, Paul Flicek, Rishi Nag, Emily S Wong, John Blangero, Thomas D Dyer, Marina Bogomolov, Yoav Benjamini, George M Weinstock, Ken Dewar, Chiara Sabatti, Richard K Wilson, J David Jentsch, Wesley Warren, Giovanni Coppola, Roger P Woods, Nelson B Freimer. 2017. "Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate.." Nat Genet, Volume 49, Issue 12, pp. 1714 - 1721.1546-1718https://hdl.handle.net/2144/28906Published in final edited form as: Nat Genet. 2017 December ; 49(12): 1714–1721. doi:10.1038/ng.3959.By analyzing multitissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate model. This catalog contains more genome-wide significant eQTLs per sample than comparable human resources and identifies sex- and age-related expression patterns. Findings include a master regulatory locus that likely has a role in immune function and a locus regulating hippocampal long noncoding RNAs (lncRNAs), whose expression correlates with hippocampal volume. This resource will facilitate genetic investigation of quantitative traits, including brain and behavioral phenotypes relevant to neuropsychiatric disorders.p. 1714 - 1721Science & technologyLife sciences & biomedicineGenetics & heredityVervet monkeyAnimalsBrainCercopithecus aethiopsGene expression profilingGenetic variationGenome-wide association studyGenotypeHumansPhenotypePolymorphism, single nucleotideQuantitative trait lociMedical and health sciencesBiological sciencesDevelopmental biologyArticle10.1038/ng.39590000-0003-2143-9226 (Schmitt, Christopher A)