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  • Bioinformatics Analysis of Macrophages Exposed to Porphyromonas gingivalis: Implications in Acute vs. Chronic Infections 

    Yu, Wen-Han; Hu, Han; Zhou, Qingde; Xia, Yu; Amar, Salomon (Public Library of Science, 2010-12-23)
    BACKGROUND. Periodontitis is the most common human infection affecting tooth-supporting structures. It was shown to play a role in aggravating atherosclerosis. To deepen our understanding of the pathogenesis of this disease, ...
  • Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings 

    Madan, Monika; Amar, Salomon (Public Library of Science, 2008-9-12)
    BACKGROUND. Accumulating evidence implicates a fundamental link between the immune system and atherosclerosis. Toll-like receptors are principal sensors of the innate immune system. Here we report an assessment of the role ...
  • Activin A Expression Regulates Multipotency of Mesenchymal Progenitor Cells 

    Djouad, Farida; Jackson, Wesley M.; Bobick, Brent E.; Janjanin, Sasa; Song, Yingjie; Huang, George T. J.; Tuan, Rocky S. (BioMed Central, 2010-5-4)
    INTRODUCTION. Bone marrow (BM) stroma currently represents the most common and investigated source of mesenchymal progenitor cells (MPCs); however, comparable adult progenitor or stem cells have also been isolated from a ...
  • The Jacob2 Lectin of the Entamoeba Histolytica Cyst Wall Binds Chitin and Is Polymorphic 

    Ghosh, Sudip K.; Van Dellen, Katrina L.; Chatterjee, Anirban; Dey, Tuli; Haque, Rashidul; Robbins, Phillips W.; Samuelson, John (Public Library of Science, 2010-7-20)
    BACKGROUND. The infectious and diagnostic form of Entamoeba histolytica (Eh), cause of amebic dysentery and liver abscess, is the quadranucleate cyst. The cyst wall of Entamoeba invadens (Ei), a model for Eh, is composed ...
  • Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice 

    Sanoudou, D.; Duka, A.; Drosatos, K.; Hayes, K. C.; Zannis, V. I. (Nature Publishing Group, 2009-12-01)
    We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical ...
  • Giardia Cyst Wall Protein 1 Is a Lectin That Binds to Curled Fibrils of the GalNAc Homopolymer 

    Chatterjee, Aparajita; Carpentieri, Andrea; Ratner, Daniel M.; Bullitt, Esther; Costello, Catherine E.; Robbins, Phillips W.; Samuelson, John (Public Library of Science, 2010-8-19)
    The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique β-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer ...
  • A New Brief Measure of Oral Quality of Life 

    Kressin, Nancy R; Jones, Judith A; Orner, Michelle B.; Spiro, Avron (Centers for Disease Control and Prevention, 2008-3-15)
    INTRODUCTION. We developed a brief measure of the impact of oral conditions on individual functioning and well-being, known as oral quality of life. METHODS. Among older male veterans (N = 827) and community dental patients ...
  • Evidence for a "Wattle and Daub" Model of the Cyst Wall of Entamoeba 

    Chatterjee, Anirban; Ghosh, Sudip K.; Jang, Ken; Bullitt, Esther; Moore, Landon; Robbins, Phillips W.; Samuelson, John (Public Library of Science, 2009-7-3)
    The cyst wall of Entamoeba invadens (Ei), a model for the human pathogen Entamoeba histolytica, is composed of fibrils of chitin and three chitin-binding lectins called Jacob, Jessie3, and chitinase. Here we show chitin, ...
  • Risk of Tooth Loss After Cigarette Smoking Cessation 

    Krall Kaye, Elizabeth; Dietrich, Thomas; Nunn, Martha E.; Garcia, Raul I. (Centers for Disease Control and Prevention, 2006-9-15)
    INTRODUCTION. Little is known about the effect of cigarette smoking cessation on risk of tooth loss. We examined how risk of tooth loss changed with longer periods of smoking abstinence in a prospective study of oral health ...
  • Identification of Positive Regulators of the Yeast Fps1 Glycerol Channel 

    Beese, Sara E.; Negishi, Takahiro; Levin, David E. (Public Library of Science, 2009-11-26)
    The yeast Fps1 protein is an aquaglyceroporin that functions as the major facilitator of glycerol transport in response to changes in extracellular osmolarity. Although the High Osmolarity Glycerol pathway is thought to ...

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