UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions
Bulyk, Martha L.
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CitationRobasky, Kimberly, Martha L. Bulyk. "UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein–DNA interactions" Nucleic Acids Research 39(Database issue): D124-D128. (2010)
The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe <130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org.