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dc.contributor.advisorGarcia-Diaz, J. Fernandoen_US
dc.contributor.authorShin, Jane Hae Sooen_US
dc.date.accessioned2019-07-22T19:17:13Z
dc.date.available2019-07-22T19:17:13Z
dc.date.issued2019
dc.identifier.urihttps://hdl.handle.net/2144/36626
dc.description.abstractEngineering cardiac tissues has attracted increasing attention in regenerative medicine. Human cardiac tissue has a complex and unique structure with intricately embedded vasculature network, making engineering cardiac tissue a challenge. This work aims to ultimately use three-dimensional (3D) extrusion bioprinting to engineer a myocardium that closely mimics the structure of its native counterpart with an embedded sensor for monitoring. We have specifically optimized the bioprinting parameters and the bioink composition. We also modified surface chemistry in order to bind two different materials. This provides a way to chemically attach the sensor mesh to a bioprinted cardiac construct. The developed cardiac patch can be used to replace the damaged or diseased cardiac tissues with the potential for non-invasive monitoring.en_US
dc.language.isoen_US
dc.subjectBiomedical engineeringen_US
dc.titleA soft electronic-instrumented cardiac patch for minimally invasive delivery and tissue healingen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2019-06-14T16:03:48Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US


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