Longevity: translation of aging theories into action
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Healthspan describes the length of time an individual lives without disability or chronic disease. Characteristic to aging is the risk for the onset of both through a progressive accumulation of deficits in normal physiologic function. In the past, the declines associated with aging were simply accepted as inevitable. Today, longevity research has undergone a meteoric rise in popularity. This is due to several landmark studies demonstrating that what was once thought of as inevitable has potential to be delayed. This thesis aims to consolidate current theories of biochemical processes believed to underlie aging, and explore their interconnections. Furthermore, current pharmaceutical and lifestyle interventions being studied to promote longevity and target these specific pathways will be analyzed for safety and practicality for use in a primary care setting. Through a shift from symptom-based care to personalized preventative care, the goal is to maximize function into older age and empower individuals to live life to the fullest well beyond what was previously imagined.
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