Biology at Boston University is a highly integrative department, with faculty teaching and conducting research in the broad range of fields that comprise the contemporary life sciences. The department spans the full spectrum of biological sciences, ranging from cell and molecular biology to ecology and conservation biology, giving us unusual strength in integrative research that addresses questions across multiple levels of biological complexity.
Department chair: Kim McCall
Campus address: 5 Cummington Street, Room 101
All materials in OpenBU are subject to Title 17 of the U.S. Code.
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(2019-07-24)The Phoenix Islands Protected Area (PIPA), one of the world’s largest marine protected areas, represents 11% of the exclusive economic zone of the Republic of Kiribati, which earns much of its GDP by selling tuna fishing ...
(AMER INST PHYSICS, 2013-03-01)The synthetic construction of intracellular circuits is frequently hindered by a poor knowledge of appropriate kinetics and precise rate parameters. Here, we use generalized modeling (GM) to study the dynamical behavior ...
(PUBLIC LIBRARY SCIENCE, 2013-10-30)Microbial biofilms are often composed of multiple bacterial species that accumulate by adhering to a surface and to each other. Biofilms can be resistant to antibiotics and physical stresses, posing unresolved challenges ...
(2019)Microbes face a trade-off between being metabolically independent and relying on neighboring organisms for the supply of some essential metabolites. This balance of conflicting strategies affects microbial community structure ...
Emergent subpopulation behavior uncovered with a community dynamic metabolic model of Escherichia coli diauxic growth (AMER SOC MICROBIOLOGY, 2019-01-01)Microbes have adapted to greatly variable environments in order to survive both short-term perturbations and permanent changes. A classical and yet still actively studied example of adaptation to dynamic environments is ...
(PUBLIC LIBRARY SCIENCE, 2016-04-01)The complexity of metabolic networks in microbial communities poses an unresolved visualization and interpretation challenge. We address this challenge in the newly expanded version of a software tool for the analysis of ...
(NATURE PUBLISHING GROUP, 2019-01-09)Metabolic exchange mediates interactions among microbes, helping explain diversity in microbial communities. As these interactions often involve a fitness cost, it is unclear how stable cooperation can emerge. Here we use ...
Genome-driven evolutionary game theory helps understand the rise of metabolic interdependencies in microbial communities (NATURE PUBLISHING GROUP, 2017-11-16)Metabolite exchanges in microbial communities give rise to ecological interactions that govern ecosystem diversity and stability. It is unclear, however, how the rise of these interactions varies across metabolites and ...
Upon accounting for the impact of isoenzyme loss, gene deletion costs anticorrelate with their evolutionary rates (PUBLIC LIBRARY SCIENCE, 2017-01-20)System-level metabolic network models enable the computation of growth and metabolic phenotypes from an organism’s genome. In particular, flux balance approaches have been used to estimate the contribution of individual ...