Biology
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URI: http://hdl.handle.net/2144/969
Biology at Boston University is a highly integrative department, with faculty teaching and conducting research in the broad range of fields that comprise the contemporary life sciences. The department spans the full spectrum of biological sciences, ranging from cell and molecular biology to ecology and conservation biology, giving us unusual strength in integrative research that addresses questions across multiple levels of biological complexity.
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Department chair: Kim McCall
Campus address: 5 Cummington Street, Room 101
Phone: 617-353-2432
Fax: 617-353-6340
Website: www.bu.edu/biology
All materials in OpenBU are subject to Title 17 of the U.S. Code.
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High resolution spatiotemporal patterns of seawater temperatures across the Belize Mesoamerican Barrier Reef.
(2020-11-16)Coral reefs are under increasingly severe threat from climate change and other anthropogenic stressors. Anomalously high seawater temperatures in particular are known to cause coral bleaching (loss of algal symbionts in ... -
Delicate balances in cancer chemotherapy: modeling immune recruitment and emergence of systemic drug resistance
(2020)Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the mechanisms responsible are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex ... -
Single-shot 3D widefield fluorescence imaging with a computational miniature mesoscope
(American Association for the Advancement of Science, 2020)Fluorescence imaging is indispensable to biology and neuroscience. The need for largescale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional ... -
Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program
(Nature Research (part of Springer Nature), 2020-05-26)Chronic opioid usage not only causes addiction behavior through the central nervous system, but also modulates the peripheral immune system. However, how opioid impacts the immune system is still barely characterized ... -
Epistatic interaction maps relative to multiple metabolic phenotypes
(Public Library of Science, 2011-02-01)An epistatic interaction between two genes occurs when the phenotypic impact of one gene depends on another gene, often exposing a functional association between them. Due to experimental scalability and to evolutionary ... -
Microbial carbon use efficiency predicted from genome-scale metabolic models
(2019-08-08)Respiration by soil bacteria and fungi is one of the largest fluxes of carbon (C) from the land surface. Although this flux is a direct product of microbial metabolism, controls over metabolism and their responses to global ... -
Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya
(BMC, 2008-06-10)Minor alleles of the human dopamine receptor polymorphisms, DRD2/TaqI A and DRD4/48 bp, are related to decreased functioning and/or numbers of their respective receptors and have been shown to be correlated with body mass, ... -
Environmental boundary conditions for the origin of life converge to an organo-sulfur metabolism
(2019-12)It has been suggested that a deep memory of early life is hidden in the architecture of metabolic networks, whose reactions could have been catalyzed by small molecules or minerals before genetically encoded enzymes. A ... -
BowSaw: inferring higher-order trait interactions associated with complex biological phenotypes
(2019-11-12)Machine learning is helping the interpretation of biological complexity by enabling the inference and classification of cellular, organismal and ecological phenotypes based on large datasets, e.g. from genomic, transcriptomic ... -
Effects of warming temperatures on winning times in the Boston Marathon
(PUBLIC LIBRARY SCIENCE, 2012-09-26)It is not known whether global warming will affect winning times in endurance events, and counterbalance improvements in race performances that have occurred over the past century. We examined a time series (1933–2004) ...
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