Biology at Boston University is a highly integrative department, with faculty teaching and conducting research in the broad range of fields that comprise the contemporary life sciences. The department spans the full spectrum of biological sciences, ranging from cell and molecular biology to ecology and conservation biology, giving us unusual strength in integrative research that addresses questions across multiple levels of biological complexity.
Department chair: Kim McCall
Campus address: 5 Cummington Street, Room 101
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Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons (AMER PHYSIOLOGICAL SOC, 2014-09-01)Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na+ channels in OSNs to assess their role in spontaneous ...
Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice (2017-03)Surgical or genetic disruption of vomeronasal organ (VNO)-accessory olfactory bulb (AOB) function previously eliminated the ability of male mice to processes pheromones that elicit territorial behavior and aggression. By ...
Season, but not symbiont state, drives microbiome structure in the temperate coral Astrangia poculata (2017-12)BACKGROUND: Understanding the associations among corals, their photosynthetic zooxanthella symbionts (Symbiodinium), and coral-associated prokaryotic microbiomes is critical for predicting the fidelity and strength of coral ...
Temperature and symbiosis affect lesion recovery in experimentally wounded, facultatively symbiotic temperate corals (Inter-Research, 2017-04-27)The health of most reef-building corals depends upon an intracellular symbiosis with photosynthetic dinoflagellates of the genus Symbiodinium that is acutely sensitive to increasing ocean temperatures. However, distinguishing ...
(2017-05-15)Developmental and lineage plasticity have been observed in numerous malignancies and have been correlated with tumor progression and drug resistance. However, little is known about the molecular mechanisms that enable such ...
(2016-02-15)The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues ...
Each of the olfactory sensory neurons (OSNs) chooses to express a single G protein-coupled olfactory receptor (OR) from a pool of hundreds. Here, we show the receptor transporting protein (RTP) family members play a dual ...
Social interactions are often powerful drivers of learning. In female mice, mating creates a long-lasting sensory memory for the pheromones of the stud male that alters neuroendocrine responses to his chemosignals for many ...
(2016-03-25)Sequencing of exomes and genomes has revealed abundant genetic variation affecting the coding sequences of human transcription factors (TFs), but the consequences of such variation remain largely unexplored. We developed ...