A clinical and experimental study of jet injections
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Abstract
Since the jet injection was clinically introduced in 1947, little work has been done to evaluate the tissue response to the technique. The present investigation compares the tissue reaction of the jet injections to that of needle injections. The animal investigation was carried out
on 30 adult rats, divided into four groups, using a tuberculin syringe
with a 26 gauge needle on the control side and a Syrijet Mark II on the
experimental. The first group of 18 rats was injected with saline and
sacrificed two at a time immediately and at one, two, three, four, six,
twelve, twenty-four and forty-eight hours. The second group of eight
rats was injected with saline and sacrificed one at a time at two,
three, four, six, twelve, twenty-four and forty-eight hours. Prior
to sacrifice this group received intraperitoneal injections of trypan
blue at half-hourly intervals for a total of three injections and was
sacrificed half an hour after the last injection. The third group of
two rats received trypan blue injections instead of saline and were
sacrificed immediately. The fourth group of two rats was injected with
India ink and sacrificed immediately. Stereoscopic and histological
examination revealed that injected solutions invariably follow the lines
of least resistance in the connective tissues and muscles. Both
techniques demonstrate areas of hemorrhage and disruption of connective
tissue fibres and displacement of epithelial cells into the underlying
connective tissues. An acute inflammatory reaction and damaged connective tissue and muscle fibres was observed following injection
techniques. Resolution was rooted in most cases within 48 hours.
Description
Thesis (M.Sc.D.)--Boston University School of Graduate Dentistry, 1973. Oral Biology.
Bibliography included.
Bibliography included.
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