The leukocyte response during orthodontic tooth movement is primarily of monocytic origin
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Abstract
Bone is a highly dynamic connective tissue which has the ability to continuously remodel itself. [1] The major functions of bone can be summarized as follows: A) it is the major organ for calcium homeostasis, B) it acts as storage for phosphate, magnesium, potassium and bicarbonate C) it provides the soft tissue portion of the body with mechanical support, D) it is the sight of insertion for muscles (i.e., acts as a lever), and E) it is the major site of hematopoiesis in the adult. [2] Two cell types, the osteoclast and osteoblast are the mayor contributors in the turnover of bone matrix. The osteoblast secretes the matrix, which then under a well-regulated process becomes calcified to become the (partially calcified) osteoid, and finally the fully calcified bone. [3] There are two types of mature bone; cortical bone (the outer denser layer of most bones, important in support) and trabecular or cancellous bone, which is metabolically more active and contains an endosteal layer rich in cells. As bone turnover is dependent on the surface area, cancellous bone has a larger surface area than cortical bone, and will undergo turnover more rapidly. [2]
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Description
Thesis (M.Sc.D.)--Boston University. Henry M. Goldman School of Graduate Dentistry, 1995 (Orthodontics).
Includes bibliographic references (leaves 45-55).
Includes bibliographic references (leaves 45-55).
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This work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.