Novel therapeutics in the treatment of drug-resistant tuberculosis: a review
OA Version
Citation
Abstract
Mycobacterium tuberculosis is the causative agent of Tuberculosis infection (TB). TB is still endemic throughout the World and is a significant cause of morbidity and mortality, killing over 4,000 people every day. Although a number of antibiotics have been available for the treatment of TB since the late 1940s, treatment duration, drug-resistance, and barriers to effective health delivery have thwarted efforts for elimination (and eventually, eradication). Here is a compendium of several novel therapies that are being considered to address this global pandemic.