Exploration of irritable bowel syndrome pathogenesis and treatment approaches
OA Version
Citation
Abstract
Irritable Bowel Syndrome (IBS) manifests in patients through diverse symptoms, including abdominal pain, altered stool frequency, inconsistent stool consistency, and bloating. Investigating the root cause of IBS and exploring effective treatment options are crucial for advancing therapeutic approaches and providing relief to affected individuals. The current speculative pathophysiology of IBS encompasses five prominent theories: post-infection immune response, serotonin dysregulation, bacterial overgrowth, brain-gut interaction, and genetic factors. Many IBS patients opt for nonpharmacological treatments, with a focus on well-studied interventions such as exercise, diet modification, FODMAP consumption, fiber intake, and probiotic supplementation. Additionally, emerging research suggests potential benefits from alternative approaches like hypnotherapy, cognitive behavioral therapy, relaxation techniques, and acupuncture. Furthermore, the variability in IBS presentations leads to distinct treatment strategies tailored for constipation or diarrhea predominant IBS, as well as specific symptom management, particularly addressing abdominal pain. This research aims to investigate the potential pathophysiology of IBS by looking at the literature to investigate the potential theories. Furthermore, it will investigate the current treatments for IBS and their effectiveness at treating the different subtypes of IBS.
Description
2024