Effect of chlorhexidine varnish on Streptococcus Gordonii Challis biofilm formation on polystyrene plates

Date
2002
DOI
Authors
Al-Asam, Sahar M.
Version
OA Version
Citation
Abstract
Viridans streptococci, which include Strepococcus gordonii, are pioneer oral bacteria that initiate dental plaque formation. Sessile bacteria in a biofilm represent a mode of growth that is distinct from planktonic bacteria. Biofilm formation of S. gordonii Challis was characterized using an in vitro biofilm formation assay on polystyrene surfaces. Chlorhexidine has proved to be effective in the suppression of mutans Streptococci and dental caries. Varnishes containing different chlorhexidine concentrations have been developed and tested with demonstrated ant microbial effects on caries associated microorganisms such as Mutans streptococci and Lactobacilli. The objective of this study was to test the effect of different Chlorhexidine varnish on biofilm formation of S. gordonii challis on polystyrene plates. The results of the one way ANOVA (F 7,126=1 1.68; P [less than].001) test showed significant difference comparing different chlorhexidine concentrations. The mean numbers of biofilm formation with chlorhexidine were .9202[plus or minus].3304 for the varnish only, .4857[plus or minus].1564 for the .25%, .6656[plus or minus].2250, for the .5 %, .4357[plus or minus] 1388 for the 1%, .4798[plus or minus] 1498 for the 2%, .4140[plus or minus].1246 for the 4%, .6710[plus or minus].1445 for the 6% group and .5723[plus or minus].2132 for the 6% group.
Description
Thesis (M.S.D.)--Boston University, Henry M. Goldman School of Dental Medicine, 2002 (Pediatric Dentistry).
Includes bibliographical references (leaves 45-54).
License
This work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.