Development of a beam propagation method to simulate the point spread function degradation in scattering media
Files
Accepted manuscript
Date
2019
Authors
Cheng, Xiaojun
Li, Yunzhe
Mertz, Jerome
Sakadzic, Sava
Devor, Anna
Boas, David A.
Tian, Lei
Version
Accepted manuscript
OA Version
Citation
X. Cheng, Y. Li, J. Mertz, S. Sakadzic, A. Devor, D.A. Boas, L. Tian. 2019. "Development of a beam propagation method to simulate the point spread function degradation in scattering media." Optics Letters, Volume 44, Issue 20, pp. 4989 - 4992. https://doi.org/10.1364/OL.44.004989
Abstract
Scattering is one of the main issues that limit the imaging depth in deep tissue optical imaging. To characterize the role of scattering, we have developed a forward model based on the beam propagation method and established the link between the macroscopic optical properties of the media and the statistical parameters of the phase masks applied to the wavefront. Using this model, we have analyzed the degradation of the point-spread function of the illumination beam in the transition regime from ballistic to diffusive light transport. Our method provides a wave-optic simulation toolkit to analyze the effects of scattering on image quality degradation in scanning microscopy. Our open-source implementation is available at https://github.com/BUNPC/Beam-Propagation-Method.
Description
License
Copyright 2019 Optical Society of America. The final author draft of this article is being made available in OpenBU under Boston University's open access policy.