The effect of surface-active agents on sodium hypochlorite irrigating solution

Date
1986
DOI
Authors
Leclerc, Robert
Version
OA Version
Citation
Abstract
The efficacy of three surface active agents combined with NaOC1 irrigating solution was investigated. A 2.6% Hypochlorite solution was combined with different concentrations of each of three surface active agents, Benzalkonium Chloride (B.C.), Sodium Lauryl Sulfate (S.L.S.) and Tween-80 or Polysorbate-80. Surface tension was measured for each concentration of the Hypochlorite/surface active agent solutions and compared with NaOC1 2.6% alone. The stability of the hypochlorite component of the combined solutions was compared with NaOC1 2.6% alone by means of the "Available Chlorine Determination test" for a one month period. The stability of the surface active agent component was measured by means of the "surface active agent stability test" for one month. A Scanning Electron Microscope (S.E.M.) examination focused at the 5 mm, 3 mm and 1 mm levels was undertaken to evaluate the cleanliness of the canal walls of freshly extracted teeth. The clinical efficacy of the use of a surface active agent was subjectively evaluated by twelve endodontic graduate students. Results indicated that Benzalkonium Chloride was slightly better than Sodium Lauryl Sulfate at reducing surface tension, and both were significantly better than Tween-80. Benzalkonium Chloride and Sodium Lauryl Sulfate did not affect the stability of the hypochlorite component of the combinations solutions. However, Tween-80 decreased the stability of the hypochlorite component after only 48 hours. The surface active agent component of each solution tested remained stable for one month. On the S.E.M. examination, no significant differences in the cleanliness of the canal walls were found among Benzalkonium Chloride, Sodium Lauryl Sulfate and the control solution at each level of examination. Tween-80, however, was less effective at each level. Clinical use of the solution containing the surface active agent showed easier cleaning and shaping procedures evaluated by the endodontic graduate students.
Description
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Includes photographs.
Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1986 (Endodontics)
Bibliography : leaves 88-96.
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This work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.