Early detection of lung cancer using nano-nose-a review
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Published version
Date
2015
Authors
Fernandes, Melanie Patsy
Saligrama, Venkatesh
Sudarshan, B.G.
Version
Published version
OA Version
Citation
M.P. Fernandes, S. Venkatesh, B.G. Sudarshan. 2015. "Early detection of lung cancer using nano-nose-a review." The open biomedical engineering journal, Volume 9, pp. 228 - 228. https://doi.org/10.2174/1874120701509010228
Abstract
Lung cancer is one of the malignancies causing deaths worldwide. The yet to be developed non-invasive diagnostic
techniques, are a challenge for early detection of cancer before it progresses to its later stages. The currently available
diagnostic methods are expensive or invasive, and are not fit for general screening purposes. Early identification not
only helps in detecting primary cancer, but also in treating its secondaries; which creates a need for easily applicable tests
to screen individuals at risk. A detailed review of the various screening methods, including the latest trend of breath
analysis using gold nanoparticles, to identify cancer at its early stage, are studied here. The VOC based breath biomarkers
are used to analyze the exhaled breath of the patients. These biomarkers are utilized by Chemiresistors coated with gold
nanoparticles, which are found to be the most suited technique for early detection of lung cancer. This technique is highly
accurate and is relatively easy to operate and was tested on smokers and non-smokers. This review also gives as an outline
of the fabrication and working of the device Na-Nose. The Chemiresistors coated with Gold nanoparticles, show a great
potential in being an non-invasive and cost-effective diagnostic technique for early detection of lung cancer.
Description
License
Fernandes et al.; Licensee Bentham Open. Open-Access License: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.