Study of epithelial-connective tissue interaction in collagen transplantation (Part II)

Date
1975
DOI
Authors
Botero, Alejandro
Version
OA Version
Citation
Abstract
The origins of tissue specificity have been the matter of many research studies and is of much potential clinical importance (Slavkin, 1969, 1971; Rawles, 1963). The maintenance of these specificities has been demonstrated in tissue and organ culture studies (Billingham and Silvers, 1963; McLaughlin, 1968; Wessells, 1962). Tissue transplantation and wound healing studies have also reemphasized the existence of such interactions throughout the entire life of a living organism (Bjorn, 1964; Sullivan and Atkins, 1968). The primacy of either one of the two tissues involved in an interaction is difficult to define; it seems that both have important roles to play in the determination of each other's organization and differentiation. The presence of RNA-complexes at the interface of interacting tissues was demonstrated by Slavkin in 1969. Epithelium - connective tissue relationships present a good model for the study of tissue interactions. From the biologic literature it is possible to conclude that collagen has the leading role in its interactions with epithelium (Billingham and Silvers, 1967; McLaughlin, 1968). The epithelial participation is not completely clear, but it may be involved in the development of specific types of collagens and probably in its maintenance (Kallahan and Grobstein, 1965). The oral tissues offer a good experimental area for studies [TRUNCATED]
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Thesis (D.Sc.D.)--Boston University School of Graduate Dentistry, 1975. Periodontontology.
Bibliography included.
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