Comparing LASSO vault prediction models to observed vaults in implantable collamer lens post-op patients
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Abstract
BACKGROUND: ICL refractive surgery is a common refractive surgery preformed on patients who are not usually candidates for LASIK or prefer a reversible refractive surgery option. The way the ICL sits in the eye is variable and difficult to predict. There are currently several methods that attempt to predict the vault size post ICL surgery with the most accurate being ultrasound and LASSO models. The LASSO model attempts to look at data collected from non-contact testing equipment to make the testing process as streamlines and comfortable for the patient as possible. Few studies have been done comparing the different LASSO calculation methods to observed vault sizes in an attempt to determine which model is most accurate.
OBJECTIVE: The goal of this thesis is to compare the different LASSO prediction methods to determine if there is a best option for ICL vault size prediction.
METHODS: A total of 47 patients (94 eyes) were observed for this thesis. The data for a retrospective study of patients who received ICL surgery in both eyes, with out prior ocular surgery, was collected from a private practice in Boston, MA. The observed vault values of these patients at the most recent follow-up appointment will be compared to the predicted vault values from the three LASSO methods prior to surgery.
RESULTS: The data showed there was no statistically significant difference between the absolute magnitude from the observed vault size and three LASSO calculation models. The data also showed a statistically significant difference between the predicted vault sizes for all three models and the observed vault size.
CONCLUSIONS: The data from this study showed that there was no statistically significant difference between the predicted vault size from the LASSO model and the actual vault size of the participants. This demonstrated the accuracy of the prediction model. Furthermore, the data showed that the LASSO prediction of vault size was effective for one day post-surgery and beyond. The results of this study align with similar research on the topic and support the effectiveness and accuracy of the LASSO regression model when predicting vault size in ICL surgery patients.
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2025