Application and utility of full-term continuous glucose monitoring in gestational diabetes mellitus
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Abstract
Gestational diabetes mellitus (GDM) is a common complication of pregnancy that results in chronic hyperglycemia during gestation. It is commonly the result of pre-existing impaired pancreatic beta cell function that is exacerbated due to the physiological demands of pregnancy. The International Diabetes Federation estimates that GDM affects approximately 14% of pregnancies worldwide. In the United States, the true prevalence of GDM is unknown but is estimated to that up to 14% of all pregnancies in the United States are diagnosed with GDM. Glycemic management is of the utmost importance in managing gestational diabetes, as it reduces adverse maternal and fetal outcomes. Historically, self-monitored blood glucose (SMBG) has been the universal way in which blood glucose is managed during pregnancy. However, SMBG does not provide a comprehensive glycemic profile. Continuous glucose monitoring is more comprehensive, as it allows for continuous measurement of interstitial glucose. The proposed study will evaluate the utility of long-term use of continuous glucose monitoring in pregnancy and potentially reduce poor maternal and fetal outcomes.