Presumptive causes and current treatment strategies for idiopathic urticaria
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Abstract
Chronic Idiopathic urticaria, also known as chronic spontaneous urticaria (CSU) is a condition that involves recurrent wheals and angioedema without well-defined inciting factors. Significant work has been done to describe the molecular causes of CSU but a unified standard cause has not been elucidated. Most cases of CSU are well managed, but it remains a burden to a significant percent of the patient population, despite multiple treatment options. In this thesis, I am to outline the current hypothesized molecular and pathologic causes of CSU, the modern advances in treatment and the effects the condition has on quality of life world-wide.