The pathogenesis, progression, and treatment of neovascular age-related macular degeneration

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Abstract
Age-related macular degeneration is a form of blindness that targets the macula of the eye and causes progressive vision loss. Many individuals all over the world are affected by this disease with the numbers expected to only increase in the coming years. As a result, it is critical that treatment options for this disease continue to be investigated to slow or halt the progression of disease and to hopefully one day find a cure. Currently, there are numerous treatment options available including laser therapy as well as vascular endothelial growth factor antagonists. In addition, there are human cell lines being investigated as possible study tools and future treatment options or cures. Although no cure exists for this disease today, there are a number of viable treatment options available to help slow the progression of blindness in those affected, with vascular endothelial growth factor antagonists showing the most efficacy. With more research, funding, and time, it is the goal of scientists to further investigate additional options, including human cell lines, to find a cure for this debilitating disease.
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2024
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