Long-range coupling of prefrontal cortex and visual (MT) or polysensory (STP) cortical areas in motion perception

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Accepted manuscript
Date
2010
Authors
Vaina, Lucia M.
Calabro, Finnegan J.
Lin, F. H.
Hamalainen, M.
Version
Accepted manuscript
OA Version
Citation
L.M. Vaina, F. Calabro, F.H. Lin, M. Hamalainen. 2010. "Long-range coupling of prefrontal cortex and visual (MT) or polysensory (STP) cortical areas in motion perception." Biomag, pp. 197 - 201.
Abstract
To investigate how, where and when moving auditory cues interact with the perception of object-motion during self-motion, we conducted psychophysical, MEG, and fMRI experiments in which the subjects viewed nine textured objects during simulated forward self-motion. On each trial, one object was randomly assigned its own looming motion within the scene. Subjects reported which of four labeled objects had independent motion within the scene in two conditions: (1) visual information only and (2) with additional moving- auditory cue. In MEG, comparison of the two conditions showed: (i) MT activity is similar across conditions, (ii) late after the stimulus presentation there is additional activity in the auditory cue condition ventral to MT, (iii) with the auditory cue, the right auditory cortex (AC) shows early activity together with STS, (iv) these two activities have different time courses and the STS signals occur later in the epoch together with frontal activity in the right hemisphere, (v) for the visual-only condition activity in PPC (posterior parietal cortex) is stronger than in the auditory-cue condition. fMRI conducted for visual-only condition reveals activations in a network of parietal and frontal areas and in MT. In addition, Dynamic Granger Causality analysis showed for auditory cues a strong connection of the AC with STP but not with MT suggesting binding of visual and auditory information at STP. Also, while in the visual-only condition PFC is connected with MT, in the auditory-cue condition PFC is connected to STP (superior temporal polysensory) area. These results indicate that PFC allocates attention to the “object” as a whole, in STP to a moving visual-auditory object, and in MT to a moving visual object.
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