Guided tissue regeneration in endodontic periapical surgeries: a systematic review
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Abstract
BACKGROUND: Guided Tissue Regeneration has been proposed in conjunction with endodontic periapical surgeries. Several studies have examined the combination of GTR and endodontic periapical surgeries to achieve osseous healing post-surgery.
Studies examined the use of GTR in conjunction with periapical surgeries have different outcomes, methods, follow up protocols and conclusions.
The differences in the outcomes, protocols and findings of existing studies provides an opportunity for the author to evaluate, compare and assess the quality of existing studies by conducting a systematic review.
AIM OF STUDY: The aim of this research project is to examine the use of guided tissue regeneration in conjunction with endodontic periapical surgeries.
MATERIAL AND METHODS: In initial searching phase, an advanced search using PubMed, Cochrane and Embase was performed. Using the following keywords (periapical surgery, apicoectomy, guided tissue regeneration, grafting materials, osseous healing, grafting in endodontics) the initial search yields to 478 studies.
Secondary screening was performed to exclude duplicate studies and irrelevant literature.
In advanced phase, after applying our exclusion criteria (studies in languages other than English, studies on animals, in- vitro literature and irrelevant studies) our search result will narrow down to 16 studies to be reviewed. Each article then was evaluated and summarized thoroughly for the next step. A flowchart was made to illustrate the process.
QUALITY ASSESSMENT: JBI Critical Appraisal scale was used to evaluate the quality of each study.
CONCLUSION: Based on this review, there is no solid agreement that guided tissue regeneration will significantly change the outcome of Endodontic Surgeries.