Investigating the history of cancer and its impact on multiple myeloma treatment methodologies and the emergence of monoclonal antibody maintenance therapy: daratumumab (DARA) a systematic review of the literature
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Abstract
This thesis paper addresses the general history, epidemiology and pathogenesis of cancer, specifically defining a prevalent and incurable subtype of cancer, multiple myeloma (MM), and its sequelae within the human body while outlining the evolution of various categories of therapy used for the treatment of cancer and its impact on our contemporary understanding of this disease. In summary, the intent of this composition aims to feature the recent emergences in treatment methodologies, explicitly investigating the utilization of monoclonal antibodies against multiple myeloma and highlighting a promising new drug known as daratumumab (DARA) and the science behind its unique anti-cancer mechanisms, both solo and in tandem with other known cancer drug therapies, and its latest achievements in clinical trials.
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2024