Biological evaluation of phema for a one-step pulpotomy precedure in primate teeth
Date
1984
DOI
Authors
Wu, Feng Cheng
Version
OA Version
Citation
Abstract
This study was an attempt to develop a new pulpotomy technique based on (1) the use of a biocompatible plastic poly-2-hydroxyethyl methacrylate (pHEMA), and (2) the ability of the pulp to repair itself after injury.
Twenty-seven teeth from seven Rhesus monkeys were utilized in this study. PHEMA was polymerized in situ by ultra-violet light and covered with composite resin in a one-step pulpotomy procedure. Formocresol, zinc oxide-eugenol, and composite resin treatments served as controls. Teeth were extracted for histologic examination after periods ranging from one day to 134 days. Histologic examination of pHEMA-treated teeth showed a range from vital pulp tissue to a few samples which showed edema, hemorrhage, complete or partial loss of pulpal tissue, and pulpal atrophy. Virtually no inflammatory changes were found.
Because of the limited number of animals and teeth in each time interval, and some technical problems encountered, firm conclusions cannot be drawn regarding the ultimate value of pHEMA pulpotomies. However, in view of the few successes after fairly long periods it is likely that a basis for the concept of pulpal healing in the presence of pHEMA exists. Further experiments and refinement of the pHEMA procedures are clearly warranted.
Description
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Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1984, (Oral Biology)
Bibliography: leaves 46-56.
Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1984, (Oral Biology)
Bibliography: leaves 46-56.
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This work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.