Effect of tooth movement and decortication on alveolar bone turnover
Date
2009
DOI
Authors
Kelson, Christopher Lee
Version
OA Version
Citation
Abstract
Orthodontic tooth movement is a non-pathologic inflammatory sequence of events that involves the recruitment of multiple types of cells which are responsible for alveolar bone modeling. Various methods have been tested to enhance the rate of the orthodontic tooth movement. Few of these techniques resulted in biologically acceptable outcomes and clinical success. Selective alveolar bone decortication has been shown to increase the rate of bone turnover resulting in shorter treatment time. The mechanism of action of this technique is not fully clear.
PURPOSE: The purpose of this study was to compare the effects of alveolar decortication on alveolar trabecular bone turnover as a function of time with and without tooth movement.
METHODS: Sprague-Dawley rats (n=56) were divided into 3 subgroups: tooth movement only (TM), corticotomy only (CORT), and corticotomy plus tooth movement (CTM). The time points were 3 days, 7 days, 14 days, 21 days and 42 days. The rats were sacrificed and the target area was evaluated histologically to analyze the trabecular bone and PDL changes. The analyses were made over time and across the various groups. Each animal served its own control (C) where the left side was the experimental side and the right side did not receive any treatment.
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Description
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Thesis (MSD) --Boston University, Goldman School of Dental Medicine, 2009 (Department of Orthodontics and Dentofacial Orthopedics).
Includes bibliographic references: leaves 41-46.
Thesis (MSD) --Boston University, Goldman School of Dental Medicine, 2009 (Department of Orthodontics and Dentofacial Orthopedics).
Includes bibliographic references: leaves 41-46.
License
This work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.