Silicon-based nanochannel glucose sensor
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Published version
Date
2008-01-07
Authors
Wang, Xihua
Chen, Yu
Gibney, Katherine A.
Erramilli, Shyamsunder
Mohanty, Pritiraj
Version
OA Version
Citation
Xihua Wang, Yu Chen, Katherine A Gibney, Shyamsunder Erramilli, Pritiraj Mohanty. 2008. "Silicon-based nanochannel glucose sensor." Appl. Phys. Lett. 92, 013903 (2008); https://doi.org/10.1063/1.2832648
Abstract
Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The differential conductance of silicon nanowires, tuned with source-drain bias voltage, is demonstrated to be sensitive to the biocatalyzed oxidation of glucose. The glucose biosensor response is linear in the 0.5–8mM concentration range with 3–5min response time. This silicon nanochannel-based glucose biosensor technology offers the possibility of high density, high quality glucose biosensor integration with silicon-based circuitry.
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© 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.